Boss fights and how the guides beat them
The published route fights Bruno twice, Charlotte, the Sister of Mercy and Marlowe. Prepare ammunition and repair melee weapons before entering an arena; story chase scenes use different rules.
What I checked
The phases below summarise PowerPyx's full walkthrough and trophy roadmap, checked on 14 October 2026. Charlotte's fire tactics are also described in GamerBlurb's fight guide.
Bruno: mansion and second fight
In the mansion basement, keep moving away from his grab while dealing damage. The room is small and the first fight can consume substantial ammunition; repair beforehand. Winning earns Come to Daddy.
The later factory fight earns Come Here, Damn You, I Want to Touch You. PowerPyx recommends igniting Bruno and firing the shotgun at close range when safe. At half health he moves through a wall opening; follow to continue the fight.
Charlotte: arena rather than chase
Loot the arena before enemies spawn. Avoid the charge, use the police car to keep space and use available fire. Dragon Breath shotgun ammunition is an optional source of fire, not a mandatory unlock.
Defeating her earns Heart on Fire. Collect the heart for Sunny and the crown from the body to sell. Earlier Charlotte encounters must be escaped; they are not this arena fight.
Sister of Mercy: red phases
Use ranged weapons while she flies around. Stop attacking and dodge when she throws knives. At roughly two-thirds and one-third health the arena turns red; after a delay she moves toward you.
Damage her during the approach until she falls, then use the prompted Hellchains action on her. Hellchains is your required action in this phase, not an attack she summons. Collect her heart and the whip after victory.
Marlowe: expose the real body
Shoot the three bodies on his back to stun the monster. Use Hellchains to open its mouth and reveal Marlowe, then attack the exposed body with the shotgun. At half health the fight moves to another part of the arena; repeat the weak-point sequence.
When prompted, finish with the Genesis Configuration. Go to Hell! unlocks here. Return the heart to Sunny before the final ritual and ending choice.
Questions
Is Leviathan a boss?
Leviathan is a lore figure and a late choice, not one of the four named fights above. See the Leviathan page.
Keep reading
Sources
- PowerPyx walkthrough — Both Bruno fights, Sister phases and Marlowe weak points.
- PowerPyx roadmap — Story trophy conditions.
- GamerBlurb Charlotte — Charlotte arena fire tactics.